First the passive and powered splitters will work with FIOS but not MOCA.
Second passive splitter are non-powered so when they split the signal there is drop in signal strength. If you have 10db coming into a 4 way splitter you will have 2.5db going out each of the ports on the splitter. Powered premium splitters will not have this issue. Whatever the incoming signal strength is all the outgoing ports will have the same strength. So if you have 1x8 premium splitter with 10db signal strength going in then you will have 10db signal strength going out of each of the 8 ports.
If you have a large number of locations, a long distance run, or a weak signal to start with then you should be using a powered splitter to compensate.
The less splitters the better. If you can home run everything back to a signal location that is ideal. It is better to use one big splitter than several smaller ones. I would recommend you use a C5002-0G0 1x2 splitter to feed a 1x16 powered splitter (47693-01P) and a 1x8 powered splitter (47693-8P). And if any of the longer runs still have a signal issue you would need to use a amplifier on those runs to boost the signal.